[Several parameters of the state of the nervous, immune and endocrine systems in newborn rats exposed to irradiation during the preimplantation period of embryogenesis]. / Nekotorye pokazateli sostoianiia nervnoi, immunnoi i éndokrinnoi sistem u novorozhdennykh krys, podvergshikhsia oblucheniiu v doimplantasionnyi period émbriogeneza.

Protracted prenatal irradiation of animals at the preimplantation stage of embryogenesis is shown to produce disturbances in the development of regulation systems, with their consequences persisting up to sexually mature period of postnatal life. Unknown before, these effects of preimplantation irradiation give the experimental confirmation to the main statement of the previously proposed theoretical concept of the "systemic teratogenesis": the ultimate effect of prenatal irradiation is a distortion of the structure of postnatal neuroimmunoendocrine regulation in the direction of overdevelopment of its endocrine component with the following coadaptive underdevelopment of the nervous and immune components.

[Short- and long-term immune status in people after radiation injury as a result of the accident at the Chernobyl Nuclear Power Station]. / Sostoianie immunnogo statusa u liudei v blizhaishie i otdalennye sroki posle luchevogo porazheniia v rezul'tate avarii na Chernobyl'skoi AES.

Humoral and cellular factors of the immune system of 133 subjects injured in the Chernobyl accident were studied during first 1.5-2 months after radiation, 5-17 months and 3 years after they suffered acute radiation sickness (I-IV degree). Significant disorders in the immune system correlating with the severity of the disease were recorded. In late terms certain shifts persisted in the immune status of subjects who had suffered acute radiation sickness, II and III degree.

[Microbiological and immunological disorders in acute radiation disease patients, victims of the Chernobyl AES accident]. / Mikrobiologicheskie i immunologicheskie narusheniia u bol'nykh ostroi luchevoi bolezn'iu, postradavshikh pri avarii na Chernobyl'skoi AES.

As many as 138 patients with acute radiation sickness, grades O-IV, were examined over time. It has been revealed that disorders in microecology and humoral immunity agreed well with the severity of radiation damage.

[The anti-infective action of immunoglobulins administered at delayed times after irradiation]. / Antiinfektsionnoe deistvie immunoglobulinov v obluchennom organizme pri otsrochennom primenenii.

In experiments with CBA and CBA X C57Bl(F-1) mice it was shown that the radio-protective efficacy and the anti-infectious influence of homo- and heterologous immunoglobulin (IG) applied one, two and three times in the period from 4h to 9 days following irradiation with doses of LD80-95/30. This was displayed by the increased survival rate and normalization of intestinal microflora in treated animals in comparison with untreated ones. Heterologous IG administered at varying times (5 to 20 days) after irradiation with the dose of 4.8 Gy increased the resistance of treated mice to infection with living E. coli culture.